C29H26ClFN4O4S.2(C7H8O3S).H2O

A receptor TK inhibitor targetingthe ErbB-1 and ErbB-2 subtypes.

C31H33N5O4.C2H6O3S

Vascular kinase inhibitors, used to treat idiopathic pulmonary fibrosis, can also inhibit angiogenesis, which can be used to assist cancer treatment.

C26H34ClN6O2P

An effective ALK inhibitor with IC50 of 0.62 nm can overcome crizotinib resistance mediated by l1196m mutation.

C29H39ClN7O2P

A tyrosine kinase receptor (MERTK) inhibitor can be used in combination with epidermal growth factor receptor (EGFR) inhibitors in cancer treatment.

C24H25ClFN5O3.2(C4H4O4)

A new generation of oral small molecule tyrosine kinase inhibitor (TKI) is an irreversible ErbB family blocker, which can act on the whole ErbB family including EGFR. Different from the first generation reversible egfrtki, afatinib will irreversibly bind to EGFR, so as to close the signal pathway of cancer cells and inhibit tumor growth.

C21H15ClF4N4O3.H2O

An oral multi kinase inhibitor, which can signal pathways such as RAF, kit, RET, PDGFR, VEGFR1 and Tie2. It is used to treat metastatic colorectal cancer and gastrointestinal stromal tumor.

C22H26ClN7O2S.H2O

Dasatinib is an oral potent oncogenic kinase inhibitor, which can block signal of cancer cell replication acceleration.

C17H21N6O4P

Anticancer drug, an effective Jak1 / 2 inhibitor

C16H20N7O6PS

C21H23N5O3S

A selective Jak1 inhibitor

C16H20N6O.C6H8O7

A Janus kinase inhibitor

C20H19D3N8O3

a highly potent and selective allosteric inhibitor of TYK2.

C29H31N7O3

Oral small molecule SRC inhibitor

C25H30N6O2

Kinase inhibitors targeting FGFR

C30H34N4O2.HCl

Highly selective and effective anaplastic lymphoma kinase (ALK) inhibitors